Performance Verification Test (PVT)

The USP Performance Verification Test (PVT) assesses the suitable performance of apparatus used in dissolution testing. This assures reliability of dissolution results that reflects the quality of the drug product and not the condition of the test equipment. As such, the PVT in USP General Chapter <711> Dissolution is a core building block for dissolution instrument qualification.

The PVT appraises the suitable performance of the entire apparatus. By using standardized materials and procedures, your laboratory can compare results from your instrument with other laboratories worldwide. Results that do not meet the acceptance criteria can indicate the improper operation of the dissolution assembly, deviation from the procedure, or an error in conducting the test.