USP’s qNMR Automated Software Solution, Delivered by Mestrelab

USP-ID: Streamlined NMR analysis for your lab

Interpreting NMR data can be challenging, particularly detecting impurities and managing overlapping peaks. Whether you’re an experienced scientist or new to NMR, USP-ID simplifies complex workflows, allowing your team to quickly and easily get answers to important questions​ such as:

  • What materials are present in my sample? ​
  • Are there any impurities in my sample?
  • How pure is my sample?
  • How much of each material is present?

USP-ID provides an easy-to-use platform for detailed chemical analysis. This one-click, automated software solution identifies, quantifies, and labels a wide range of chemical components in simple solutions and complex mixtures. Developed by USP and delivered by Mestrelab Research, it leverages the capabilities of quantitative NMR (qNMR) for analysis.

Request a demo for USP's qNMR automated software solution in your lab

Why USP-ID?

  • Easy chemical & impurity identification: Automatically detect, identify, and quantify chemical components and impurities quickly, streamlining qNMR for users of all levels.
  • Resolve complex spectra: Using advanced quantum-mechanical models and USP Reference Standards, identify and quantify chemicals, even in complex mixtures with overlapping peaks.
  • Customize your libraries locally: Utilize USP-ID’s automation with databases stored locally. Integrate your custom models and libraries. USP also provides support for developing custom models to address your specific needs.

USP-ID Workflow

Features of USP-ID

  • Automatic chemical ID: The Confirm ID workspace identifies chemical samples by screening them against a comprehensive reference library. Choose a targeted workflow with pre-selected references or a non-targeted workflow to identify unknown compounds, for fast and flexible analysis.
  • Find impurities: The Find Impurities feature automatically detects and labels signals that don’t match the confirmed chemical profile, eliminating the need for manual spectral scans. Select a signal in the workspace, and it will be highlighted in the spectral viewer for a guided review of impurities.
  • Automatic quantitation: The Determine Quantities feature calculates concentrations by comparing matched signals to a known internal standard, eliminating manual signal integration.
  • Report generator: Easily generate comprehensive PDF reports that include detailed analysis steps, tables of matched compounds, and purity values. These reports are designed for easy sharing and review and provide clear documentation of your analysis results.
  • Customizable libraries: Create locally stored, custom libraries for use across all automated analyses, while maintaining control of your proprietary data. Add new models or libraries through the library manager for flexible, tailored analysis.
  • Integrated workspace: Monitor real-time results from all steps—Confirm ID, Find Impurities, and Determine Quantities in one solution.

Quality standards integration

USP-ID aligns with USP’s updated quality standards, enhancing the power of NMR and qNMR as reliable analytical techniques. These standards help ensure your analyses meet the highest benchmarks for accuracy, reproducibility, and consistency, helping you maintain product quality and safety. These standards include USP-NF General Chapters <761> Nuclear Magnetic Resonance Spectroscopy, and <1761> Applications of Nuclear Magnetic Resonance Spectroscopy.

To further support stakeholder adoption of NMR and qNMR, USP Education offers free training and courses, including “Drug Quality Control Applications for qNMR.”

The integration of USP-ID into Mnova does not imply approval, endorsement, or certification by USP of Mestrelab products, nor does it imply that any other brand or product was judged to be unsatisfactory or inadequate. As a standard setting organization, USP avoids providing endorsements that create conflicts of interest that interfere or appear to interfere with its impartiality and objectivity.