USP Reference Standards

Recognized globally, USP Standards accelerate the pharmaceutical drug development process and increase confidence in the accuracy of analytical results. USP Standards are built on deep science, provide a high degree of analytic rigor and are accepted by regulators around the world. USP Standards support every stage of drug development and manufacturing, saving time and resources which contribute to the acceleration of the development of quality medicines.

The use of USP Standards (Pharmacopeial Reference Standards and Pharmacopeial Documentary Standards Method) enables companies to operate with a high level of certainty and confidence, reducing the risk of incorrect results that could lead to unnecessary batch failures, product delays, and market withdrawals.


Reference Standards Catalog

USP currently offers more than 3,500 Reference Standards—highly characterized specimens of drug substances, excipients, food ingredients, impurities, degradation products, dietary supplements, compendial reagents and performance calibrators. Click below to download the full list.


new reference standards

New Releases

Access the USP Store to see a list of new product releases.

Upcoming reference standards releases

Upcoming Releases

See a list of upcoming product releases.

Quality Solutions Sheets

A compilation of documentary standards and physical materials related to a drug substance or product – all in one place.

USP–NF online

USP–NF Updates

See USP–NF and Pharmacopeial Forum updates.

Featured Products & Solutions

Performance Verification Testing

Performance Verification Testing

A new standard for Performance Verification Testing (PVT) is now available.


Direct Oral Anticoagulants

Standards and solutions for anticoagulant drug development.



USP offers a growing catalog of Nitrosamine impurities.