Dissolution Performance Verification Testing (PVT)

This page provides updated information and links related to Dissolution Performance Verification Testing (PVT). For your convenience, current and past USP specification standards are posted.

Updates and Relevant Links

• Pharmaceutical Research Publishes Prednisone Tablets P1I300 Paper
• Free Webinar on Dissolution Performance Verification Testing
• Updated FAQs for Prednisone Tablets (posted August 24, 2010)
• Dissolution Toolkit Version 2.0 (posted April 1, 2010)
• Calculation Tool for the Performance Verification Test (PVT) of Dissolution Assemblies (posted October 5, 2011)

Specifications for PVT Tablets

(Reference Standard Ranges for Dissolution Performance Verification included where appropriate)

USP Prednisone Tablets Reference Standards (Performance Verification Tablet, Disintegrating)

• Lot Q1L136 (Current Lot)
• Lot Q0H398
• Lot P1I300
• Update Lot P0E203 (effective July 16, 2007)
• Lot P0E203
• Update Lot O0C056 (effective December 6, 2004)
• Lot O0C056
• Lot N

USP Chlorpheniramine Maleate Extended–Release Tablets (Drug Release Calibrator, Single Unit)

• Removal of PVT Qualification for Apparatus 3 (effective February 1, 2012)
• G1J218
• Customer letter regarding transition from lot G0B259 to G1J218
• Update Lot G0B259 (effective September 30, 2004)
• Lot G0B259

USP Salicylic Acid Tablets Reference Standards (Dissolution Calibrator, Nondisintegrating). As of December 1, 2009 not a Compendial Requirement.

• Lot Q0D200
• Lot P0C404
• Lot O