Interim Revision Announcements (IRAs)

Interim Revision Announcements (IRAs) are published in Pharmacopeial Forum (PF) as proposed IRAs. After a 90-day notice and comment period and approval by the relevant USP Expert Committee, IRAs are posted as official text in this location of the USP website, and are incorporated into the next available official publication (USP–NF or Supplement). Official IRAs are no longer published in PF. The PF posting dates, comment deadlines and IRA posting and official dates are outlined in the chart below.


Proposed IRA Posting
Date in PF

Public Comment Due Date

Final IRA Posting Date on Web

IRA Official Date

40(4)July 1, 2014Sep 30, 2014Nov 21, 2014*Jan 1, 2015
40(5)Sept 2, 2014Nov 30, 2014Jan 30, 2015Mar 1, 2015
40(6)Nov 3, 2014Jan 31, 2015March 27, 2015May 1, 2015
41(1)Jan 2, 2015Mar 31, 2015May 9, 2015Jul 1, 2015

*Posting date adjusted to accommodate Thanksgiving Holiday.

Monograph names listed below link to the combined IRA posting in which the announcement appeared. Beginning in March 2011, each monograph name will link to the individual IRA.

Interim Revision Announcement IconNew IRAs

All Posted IRAs

IRAs by Publication

The below organization of IRAs was discontinued in March 2011, but is included for historical purposes.

Official IRAs in PF 36

Official IRAs in PF 35

*The <121> Insulin Assays Interim Revision Announcement that was posted on January 30, 2015 was missing the definition for Vu in the Assay section.  A corrected version of the Interim Revision Announcement was uploaded to the website on February 27, 2015.