<644> Conductivity of Solutions

Type of Posting: Notice of Adoption of a new Harmonized Standard
Posting Date: 28–September–2018
Targeted Official Date: 01–August–2019
Expert Committee: General Chapters—Chemical Analysis
Coordinating Pharmacopoeia: USP

A new harmonized standard for measuring conductivity of solutions has been approved by the Pharmacopeial Discussion Group (PDG) as described in the PDG sign-off cover sheet. Having reached Stage 4 of the PDG process, General Chapter <644> Conductivity of Solutions has been formally approved by the General Chapters—Chemical Analysis Expert Committee in accordance with the Rules and Procedures of the 2015–2020 Council of Experts.

This new standard provides information on how to apply electrical conductivity measurements of fluid solutions, including pure fluids. This chapter is intended for fluid applications when conductivity is used to measure, monitor, or control chemical dispensing, chemical purity, ionic concentration, and other applications where the ionic character of the fluid needs to be known or controlled. Applications include, but are not limited to, solutions that may be used in clean-in-place, chromatography detection, ionic solution preparations, endpoint detection, dosing, fermentation, and buffer production.

The <644> Conductivity of Solutions General Chapter will be incorporated into and become official with the First Supplement to USP 42-NF 37.

Should you have any questions about the <644> Conductivity of Solutions General Chapter, please contact Antonio Hernandez-Cardoso (301-816-8308 or ahc@usp.org). For any questions about the PDG and its processes, please see the Pharmacopeial Harmonization Web page or contact Richard Lew (240-221-2060 or rll@usp.org).