Dissolution and Drug Release Tests

Contact Information

Reference Standards: rstech@usp.org

Consultas Cientificas en Espanol: uspespanol@usp.org

Customer Service: custsvc@usp.org

Dissolution and drug release tests are in vitro tests that measure the rate and extent of solution formation of a solid state from a drug product. They are used, in most cases, as a measure of drug product performance in vitro. USP provides procedures and other information on the dissolution or drug release testing of different dosage forms organized along routes of administration. Learn about the USP dissolution test.

Procedures for Qualification of
Apparatuses 1 and 2

This document provides a detailed description
of best practices gained by USP Laboratory
for mechanical calibration and PVT of USP
basket and paddle dissolution apparatuses
and test assemblies.

The USP Dissolution Methods Database

The database contains test conditions
and features helpful search features.

Dissolution FAQs

Get answers to frequently asked questions
about Dissolution and PVT.