The USP Dietary Supplement Verification Process

USP conducts a rigorous process of tests and reviews before awarding the USP Verified Mark to a dietary supplement that a manufacturer voluntarily submits for verification. The process includes the following steps:

  • Experienced USP scientists test supplement products to ensure that they meet USP standards for quality, purity, and potency. This includes testing dietary supplement products and their ingredients against dietary supplement standards found in The United States Pharmacopeia and The National Formulary (USP–NF).
  • USP conducts a thorough manufacturing and quality control/product document review.
  • USP performs an on-site manufacturing facility audit for compliance with USP standards and FDA current Good Manufacturing Practices (21 CFR Part 111).
  • After a product is verified, USP performs random, off-the-shelf testing to confirm that it continues to meet USP's strict standards.

For complete details, see the USP Dietary Supplement Verification Program Manual for Participants and the Mark Usage Manual.